Metabolites and Mysteries of Magic Mushrooms

The year is 2026. You find yourself at the pharmacy poised to collect your psilocybin prescription. The pharmacist hands you an orange pill bottle containing a single 25 milligram pill. Your mind drifts back to your recreational psychedelic days weighing out 3.5 grams of dried psilocybe AKA magic mushrooms and you wonder if you’ve been given a microdose.

At 25 mg, this aligns with the standard therapeutic dose used in clinical trials that test psilocybin’s efficacy in the treatment of various mental illnesses. It isn’t a microdose, it’s just a synthetic one. Psilocybin synthesized in the lab by chemists rather than in the mushroom by the mushroom.

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