How to predict protein structures with AlphaFold 2 using ColabFold

The structure of a protein, that is the spatial disposition of all its atoms, determines its function, interaction with other molecules, regulation, stability, and all other kinds of relevant properties. Knowing a protein’s structure is therefore essential to understand how it works, how we can block or activate its activity with a drug, how we can tune its function or stability for a biotechnological application, etc. That’s all relevant as fundamental knowledge and for applications in medicine and processes. Protein structure modeling is the process of predicting the three-dimensional structure of a protein (the “target” protein) from its amino acid sequence. Methods for protein structure prediction are essential in modern biology, because a huge number of proteins are not amenable to the kind of experimentation required to solve their structures: some cannot be produced in stable forms in solution, others can be produced but they they do not crystallize, or they are too small for some techniques, or too big for others, etc. <a href="https://medium.com/advances-in-biological-science/how-to-predict-structures-with-alphafold-2-using-colabfold-89d858d2d356">Visit Now</a>