Tag: Somatic

Beyond the Somatic Mutation Theory of Cancer

“The problem lies not so much in developing new ideas, but in escaping from old ones” John Maynard Keynes By 2009, it was clear that the somatic mutation theory (SMT) — that cancer was simply a random collection of genetic mutations — was leading exactly nowhere. Billions ...

Announcing TenSixteen Bio, a Pioneering Company to Pursue the Biology of Somatic Mosaicism, Starting with CHIP

As a hematologist, I am fascinated with our blood system and how certain blood cells develop cancer through mutations in their genetic code. On the other hand, I have often seen how these mutations drive the deadly nature of cancer. In my early years as a physician, I took care of a 30-year-old woma...