Tag: Modified

The inventors have engineered modified integrin polypeptides by introducing cysteine mutations to enable covalent disulfide bond formation between the α and β subunits. This prevents subunit dissociation and enables formation of stable, crystallizable integrin heterodimers. The cysteine s...

One of the most bizarre and puzzling aspects of nature is the existence of dark matter: a massive species of particle whose effects are easily seen, but that has eluded every attempt at direct detection thus far. The cosmic need for dark matter is undeniable, although many hold o...