Tag: linked

Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism

The paper describes a new method called “tRNA display” to engineer orthogonal aminoacyl-tRNA synthetases that can attach non-canonical monomers (ncMs) to tRNAs, independent of whether the ncMs can be polymerized by the ribosome. Current methods rely on the ncM being a ribosomal substrate...

Against Linked Open Data

It is a truth universally acknowledged, that an organization in possession of good Data, must want it Open (and indeed, Linked). Well, I call bullshit. Most cultural heritage organizations (like most organizations) are terrible at data. And most of those who are good at collecting it, very rarely...