Article Review — Do Bacteria Mutate Intentionally or Randomly?
<p> In the 1940s, the scientists Salvador Luria and Max Delbrück conducted an experiment to show that bacteria mutated spontaneously that won a Nobel Prize in 1969. Their findings have been consistently used to explain that bacteria can develop resistance to antibiotics/drugs that have not been developed yet.</p>
<p>The phenomenon that had led to the scientists’ venture is then introduced. When bacteria are living in a nutrient broth, it appears to be cloudy due to the abundance of colonies present. Introducing phages (viruses that kill bacteria) makes the broth clear as many bacteria are killed off. Maintaining optimal conditions for growth after that returns the cloudy appearance from earlier. Is this because the bacteria developed resistance to the phage after encountering it or because of a random resistant variant proliferating?</p>
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