Biggest medical advances in 2023
<h2>Green light for CRISPR gene editing</h2>
<p>On December 8, the U.S. Food and Drug Administration approved <a href="https://www.sciencenews.org/article/first-crispr-therapy-sickle-cell-fda" rel="noopener ugc nofollow" target="_blank">the world’s first CRISPR/Cas9 gene-editing therapy</a> (<em>SN: 12/8/23</em>). The treatment, called Casgevy, targets sickle cell disease by helping patients produce healthy hemoglobin. In people with the disease, hemoglobin is abnormal, causing red blood cells to become hard and crescent shaped, which can block blood flow. By March 2024, the FDA will decide whether the same therapy can be used to treat beta-thalassemia, a disorder that reduces hemoglobin production.</p>
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