Patients would take around a tenth of the amount it takes to become hallucinogenic with doses carefully managed by a trained psychiatrist. People with a family history of psychosis and schizophrenia can not risk taking psychedelics due to a rare side effect that causes permanent psychosis.
Humans have a long history of experimenting with foods and plants to alter consciousness. Those traditional uses inspired today's common medicines; opium for pain, artemisinin as antimalarial, and anti-cancer drugs derived from Catharanthus roseus and Taxus baccata. The following ten are examples of common spices used for their effects on both the mind and spirit.