Tag: Bioavailable

Pyridoxal 5 Phosphate (P5P): Highly Bioavailable Vitamin B6

Pyridoxal 5’-phosphate (P5P) is the active coenzyme form of Vitamin B6 which can be directly utilized by the body without conversion. There are several compounds that are commonly referred to as B6 including Pyridoxine, Pyridoxal, Pyridoxamine, and their respective 5`-phosphate forms. These ar...

De novo development of small cyclic peptides that are orally bioavailable

The paper describes a method to develop small cyclic peptides that can bind to therapeutic targets with high affinity and specificity, and also be orally bioavailable. This could allow cyclic peptides to be developed as oral drugs. The method involves a two-step combinatorial synthesis approach to g...