How do psychedelics affect the brain?

In recent years there has been a renaissance of research into the use of psychedelics for the treatment of a wide array of psychopathologies. Mental health concerns as various as mood disorders, anxiety disorders, body-image disorders, addiction, and others have all been shown to be amenable to psychedelic therapy [<a href="https://link.springer.com/article/10.1007/s13311-017-0542-y" rel="noopener ugc nofollow" target="_blank">1</a>]. In many cases, results suggest that one or two sessions of psychedelic assisted psychotherapy can lead to lasting reduction in symptoms, even when other mainline therapies have failed. Indeed, a recent high quality double-blind study has shown the classic psychedelic drug psilocybin to be as effective at reducing symptoms of major depressive disorder as SSRIs [<a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2032994" rel="noopener ugc nofollow" target="_blank">2</a>]. These promising results have led to an increase of interest from academic, commercial, and legal entities. With all of this interest, it is increasingly likely that psilocybin will become a legal and available treatment option for individuals with depression and potentially other related issues in the coming years. <a href="https://awjuliani.medium.com/a-computational-lens-on-the-therapeutic-action-of-psychedelics-6e994220d024">Click Here</a>