Muscle Fatigue And The MCT1 Gene
<p>The onset of <a href="https://www.xcode.life/dna-and-fitness/aerobic-capacity/" rel="noopener ugc nofollow" target="_blank">muscle </a>fatigue has hampered many athletes from achieving their maximum potential. Th<a href="https://www.xcode.life/23andme-raw-data/genetic-variants-lactose-intolerance/" rel="noopener ugc nofollow" target="_blank">e lactic acid</a> buildup is a byproduct of anaerobic metabolism. Under normal activity levels, the body mostly relies on <a href="https://www.xcode.life/dna-and-fitness/aerobic-capacity/" rel="noopener ugc nofollow" target="_blank">aerobic metabolism</a> and hence lactate (another name for lactic acid) buildup is not a major concern.</p>
<p>However, with increased activity levels, specifically, when the metabolism switches from aerobic (oxidative) to anaerobic (glycolytic), as in power activities performed at high heart rates, lactate levels quickly build-up, which, if not cleared from muscles, cause fatigue and a burning sensation.</p>
<p>But how quickly lactic acid is cleared and how quickly a person feels this fatigue is also influenced by your genetics, especially the MCT1 gene. This article explains how individual differences affect the lactic acid clearance rate and muscle fatigue.</p>
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