MODELLER usage for Homology Modelling: Tutorial with codes in 5 simple steps — Part 1

<p>In simple words, let&#39;s say you have a protein molecule&nbsp;<strong>&quot;A&quot;</strong>&nbsp;that is a newly found protein, or it is a protein that is difficult to purify ( proteins are super-duper tough to purify, ufff I wish they weren&#39;t ), then we try finding a similar protein molecule to this molecule, say&nbsp;<strong>&quot;B&quot;,&nbsp;</strong>and&nbsp;<strong>based on the structure of B, we try to develop the structure of A.&nbsp;</strong>Now, I agree that the structure might not be absolutely correct, but it still helps us understand what the structure of A could look like, and further study its properties. Now typically in homology modelling, you call the protein&nbsp;<strong>&quot;A&quot;&nbsp;</strong>a target protein, because that is what we are targeting to find the structure of, and we call&nbsp;<strong>&quot;B&quot;</strong>&nbsp;a template protein because it is a template to build our target structure on it.</p> <p><a href="https://medium.com/@snippetsbio/modeller-usage-for-homology-modelling-tutorial-with-codes-in-5-simple-steps-part-1-8e83ee2ec2b7"><strong>Website</strong></a></p>