The Next Big Thing in Genomics
<h2><strong>Background and Basics</strong></h2>
<p>For decades, genetic information in humans have been compared to a baseline “reference genome.” The differences between sequenced humans and the reference genome has successfully informed thousands (if not more) studies and helped progress our knowledge of disease and therapeutics.</p>
<p>The original sequence, famously costing the more than a billion dollars, has pulled it’s weight.</p>
<p>It has issues, though. A <a href="https://www.science.org/doi/10.1126/science.abj6987" rel="noopener ugc nofollow" target="_blank">landmark study</a> of it’s own, the recently released Telomere-2-Telomere (T2T-CHM13) reference is the most complete so far, covering almost all information needed for analysis, is made up of majority Europeans ancestry.</p>
<p><a href="https://medium.com/science-stories-by-students/the-next-big-thing-in-genomics-6d702cc4a339"><strong>Website</strong></a></p>