Future of Covid: Will Schizophrenia Haunt the Next Generation?

<p>Whenever I watch horror ghost movies, I always think the characters may have&nbsp;<a href="https://www.nhsinform.scot/illnesses-and-conditions/mental-health/schizophrenia" rel="noopener ugc nofollow" target="_blank">schizophrenia</a>. If Covid-19 had occurred a generation or two earlier, I might have thought that the schizophrenia character&lsquo;s mother caught Covid during pregnancy.</p> <p>This idea struck me when a commenter on my&nbsp;<a href="https://medium.com/microbial-instincts/immunity-debt-vs-theft-what-explains-the-post-lockdown-infection-rebounds-2a218283936e?sk=0dac5b838d199b8b524d82f214dd214d" rel="noopener">previous article</a>&nbsp;shared a new study, showing that schizophrenia-specific genes upregulated in pregnant mothers with Covid-19 vs. no Covid.&nbsp;<a href="https://www.nature.com/articles/s41467-023-38140-1" rel="noopener ugc nofollow" target="_blank">This study</a>&nbsp;isn&rsquo;t to be taken lightly. It was published in a prestigious journal,&nbsp;<em>Nature Communications</em>, led by world-renowned scientists in the schizophrenia research field.</p> <h1>A backdrop on schizophrenia</h1> <p>A patient affected with schizophrenia can&rsquo;t differentiate between imagined thoughts from reality. As a result, they may&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678179/" rel="noopener ugc nofollow" target="_blank">believe in</a>&nbsp;supernatural beings like ghosts. Schizophrenia is a mental disorder with symptoms of delusions, hallucinations, and other behavioral anomalies.</p> <p>Schizophrenia typically occurs earlier in men (late adolescence to early twenties) than in women (late twenties).&nbsp;<a href="https://www.who.int/news-room/fact-sheets/detail/schizophrenia#" rel="noopener ugc nofollow" target="_blank">About</a>&nbsp;<a href="https://academic.oup.com/epirev/article/30/1/67/621138?login=false" rel="noopener ugc nofollow" target="_blank">0.3&ndash;0.7%</a>&nbsp;of the adult population has schizophrenia. Its&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745031/" rel="noopener ugc nofollow" target="_blank">risk</a>&nbsp;<a href="https://academic.oup.com/bmb/article/73-74/1/1/332342" rel="noopener ugc nofollow" target="_blank">factors</a>&nbsp;include being male, pregnancy/birth complications, high parental age, early traumatic life events, and social isolation.</p> <p>But none of these factors fully explain or are specific to schizophrenia. Birth complications and early traumatic life events are also risk factors for&nbsp;<a href="https://www.sciencedirect.com/science/article/pii/S0165178105000508?via%3Dihub=" rel="noopener ugc nofollow" target="_blank">borderline personality</a>&nbsp;or&nbsp;<a href="https://link.springer.com/article/10.1007/s00406-004-0521-2" rel="noopener ugc nofollow" target="_blank">anxiety</a>&nbsp;disorders, for instance</p> <p><a href="https://medium.com/microbial-instincts/future-of-covid-will-schizophrenia-haunt-the-next-generation-6a5c249c1912">Visit Now</a></p>