Unlocking the Code to Faster Drug Development
<p>We seem to have a love-hate relationship with prescription drugs. They save lives every day, yet they’ve also become a source of discomfort, confusion and frustration. First, there are the side effects — which I see so often as a practicing emergency physician. When you have an infection, you take antibiotics in the hopes of killing the microscopic bad guys. What you don’t bargain for are the all-too-common nausea, vomiting or diarrhea. And then there are the diseases that could have effective drugs but don’t just because the market isn’t lucrative enough.</p>
<p>Why doesn’t the pharmaceutical industry just make more, and better, drugs? The cost to develop a new drug, prove it is safe and effective, and secure approval, can be astronomical — ranging from $10 million to $2 billion. Part of the reason it’s so expensive is that 9 out of 10 drugs are found to be unsafe or ineffective, so they don’t reach the market. Creating drugs for rare diseases is also a risky and costly investment, so some pharmaceutical companies just avoid it altogether.</p>
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