The Economics of Drug Discovery and Development are Not What You Think
<p>Simply stated, without a dramatic increase in R&D productivity, today’s pharmaceutical industry cannot sustain sufficient innovation to replace the loss of revenue due to patent expirations for successful products (Nature Reviews, March 2010). In addressing this crisis, next-generation approaches to clinical development have received disproportionate attention within industry, academia and regulatory agencies (1). At Evince, we are committed to substantially reducing the cost by increasing productivity in <strong>drug discovery </strong>via an artificial intelligence based <em>in silico</em> platform. A careful analysis reveals that the capitalized cost of discovery and preclinical development is 46% of total R&D costs, compared with 54% for clinical development (Nature Reviews, March 2010). It is counterintuitive that the cost of discovery and preclinical development should be such a large percentage of the total cost. </p>
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